| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| acs | cce_2482 | cce_2016 | cce_2482 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | Putative 3-hydroxyacid dehydrogenase. | 0.819 |
| acs | cce_2680 | cce_2016 | cce_2680 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | 0.957 |
| acs | cce_3077 | cce_2016 | cce_3077 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | AMP-dependent synthetase and ligase, probable acyl-CoA synthase. | 0.870 |
| acs | cce_3229 | cce_2016 | cce_3229 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | 0.943 |
| acs | mmsB | cce_2016 | cce_0405 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | Putative 3-hydroxyisobutyrate dehydrogenase. | 0.819 |
| acs | pta | cce_2016 | cce_3096 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | Phosphotransacetylase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. | 0.960 |
| cce_2480 | cce_2481 | cce_2480 | cce_2481 | Unknown; Contains an alpha/beta hydrolase fold. | Unknown. | 0.773 |
| cce_2480 | cce_2482 | cce_2480 | cce_2482 | Unknown; Contains an alpha/beta hydrolase fold. | Putative 3-hydroxyacid dehydrogenase. | 0.645 |
| cce_2480 | cce_3077 | cce_2480 | cce_3077 | Unknown; Contains an alpha/beta hydrolase fold. | AMP-dependent synthetase and ligase, probable acyl-CoA synthase. | 0.897 |
| cce_2481 | cce_2480 | cce_2481 | cce_2480 | Unknown. | Unknown; Contains an alpha/beta hydrolase fold. | 0.773 |
| cce_2481 | cce_2482 | cce_2481 | cce_2482 | Unknown. | Putative 3-hydroxyacid dehydrogenase. | 0.645 |
| cce_2482 | acs | cce_2482 | cce_2016 | Putative 3-hydroxyacid dehydrogenase. | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.819 |
| cce_2482 | cce_2480 | cce_2482 | cce_2480 | Putative 3-hydroxyacid dehydrogenase. | Unknown; Contains an alpha/beta hydrolase fold. | 0.645 |
| cce_2482 | cce_2481 | cce_2482 | cce_2481 | Putative 3-hydroxyacid dehydrogenase. | Unknown. | 0.645 |
| cce_2482 | cce_2680 | cce_2482 | cce_2680 | Putative 3-hydroxyacid dehydrogenase. | Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | 0.918 |
| cce_2482 | cce_3077 | cce_2482 | cce_3077 | Putative 3-hydroxyacid dehydrogenase. | AMP-dependent synthetase and ligase, probable acyl-CoA synthase. | 0.471 |
| cce_2482 | cce_3229 | cce_2482 | cce_3229 | Putative 3-hydroxyacid dehydrogenase. | Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | 0.918 |
| cce_2482 | mmsB | cce_2482 | cce_0405 | Putative 3-hydroxyacid dehydrogenase. | Putative 3-hydroxyisobutyrate dehydrogenase. | 0.927 |
| cce_2482 | pta | cce_2482 | cce_3096 | Putative 3-hydroxyacid dehydrogenase. | Phosphotransacetylase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. | 0.800 |
| cce_2680 | acs | cce_2680 | cce_2016 | Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.957 |