Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
htpGHeat shock protein Hsp90; Molecular chaperone. Has ATPase activity. (664 aa)    
Predicted Functional Partners:
dnaK3
Heat shock protein Hsp70; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 0.960
groEL1
Chaperonin 1; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
   
 
 0.956
groEL2
Chaperonin 2; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
   
 
 0.956
dnaK1
Heat shock protein Hsp70; Acts as a chaperone; Belongs to the heat shock protein 70 family.
   
 0.955
cce_2464
Hsp70-like protein; Belongs to the heat shock protein 70 family.
  
 0.948
dnaK2
Heat shock protein Hsp70; Acts as a chaperone; Belongs to the heat shock protein 70 family.
   
 0.947
groES
Chaperonin; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.
   
 
 0.921
cce_1424
Hypothetical protein.
   
 0.914
cce_3028
FKBP-type peptidyl-prolyl cis-trans isomerase.
   
 0.906
cce_5005
Hypothetical protein; Contains Helicase, C-terminal, Type III restriction enzyme, res subunit and DEAD/DEAH box helicase, N-terminal domains.
   
 0.893
Your Current Organism:
Crocosphaera subtropica
NCBI taxonomy Id: 43989
Other names: C. subtropica ATCC 51142, Crocosphaera subtropica ATCC 51142, Cyanothece sp. ATCC 51142, Cyanothece sp. BH68, Cyanothece sp. BH68K
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