STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
smfDNA processing protein. (374 aa)    
Predicted Functional Partners:
comE
Competence protein.
 
  
 0.927
cyl0021
Hypothetical protein; Contains a phosphoribosyltransferase domain.
 
 
 0.925
cce_4061
Mg chelatase-like protein.
 
 0.910
hofD
Type 4 prepilin peptidase; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue.
  
  
 0.798
cce_1521
Unknown; Contains PAS, GGDEF, EAL, Response regulator receiver, CheY-like, and PAS fold-3 domains.
  
    0.644
topA1
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
    
 0.632
cce_3023
Putative multiple antibiotic resistance (MarC)-like protein.
       0.616
cce_2104
Hypothetical protein; Contains UPF0102; Belongs to the UPF0102 family.
 
    0.604
cce_2495
DNA repair protein radC; Belongs to the UPF0758 family.
  
  
 0.599
cce_3494
Glycerophosphoryl diester phosphodiesterase; Belongs to the alkaline phosphatase family.
  
    0.575
Your Current Organism:
Crocosphaera subtropica
NCBI taxonomy Id: 43989
Other names: C. subtropica ATCC 51142, Crocosphaera subtropica ATCC 51142, Cyanothece sp. ATCC 51142, Cyanothece sp. BH68, Cyanothece sp. BH68K
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.