node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
acs | cce_3119 | cce_2016 | cce_3119 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | Na+/solute symporter; Catalyzes the sodium-dependent uptake of extracellular L- proline; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. | 0.533 |
acs | gltA | cce_2016 | cce_1900 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | Citrate synthase; Belongs to the citrate synthase family. | 0.985 |
acs | putA | cce_2016 | cce_1595 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | Bifunctional proline dehydrogenase/delta-1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family. | 0.896 |
apt | cce_3119 | cce_2298 | cce_3119 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Na+/solute symporter; Catalyzes the sodium-dependent uptake of extracellular L- proline; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. | 0.641 |
cce_0329 | cce_3119 | cce_0329 | cce_3119 | Probable sodium-dependent transporter. | Na+/solute symporter; Catalyzes the sodium-dependent uptake of extracellular L- proline; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. | 0.481 |
cce_0863 | cce_3119 | cce_0863 | cce_3119 | Na+/alanine symporter. | Na+/solute symporter; Catalyzes the sodium-dependent uptake of extracellular L- proline; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. | 0.721 |
cce_0863 | gltA | cce_0863 | cce_1900 | Na+/alanine symporter. | Citrate synthase; Belongs to the citrate synthase family. | 0.418 |
cce_0863 | putA | cce_0863 | cce_1595 | Na+/alanine symporter. | Bifunctional proline dehydrogenase/delta-1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family. | 0.436 |
cce_0948 | cce_3119 | cce_0948 | cce_3119 | ATP-binding protein of amino acid ABC transporter. | Na+/solute symporter; Catalyzes the sodium-dependent uptake of extracellular L- proline; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. | 0.611 |
cce_0948 | putA | cce_0948 | cce_1595 | ATP-binding protein of amino acid ABC transporter. | Bifunctional proline dehydrogenase/delta-1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family. | 0.524 |
cce_1185 | cce_3119 | cce_1185 | cce_3119 | Two-component hybrid sensor and regulator. | Na+/solute symporter; Catalyzes the sodium-dependent uptake of extracellular L- proline; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. | 0.488 |
cce_1185 | gltA | cce_1185 | cce_1900 | Two-component hybrid sensor and regulator. | Citrate synthase; Belongs to the citrate synthase family. | 0.420 |
cce_1185 | putA | cce_1185 | cce_1595 | Two-component hybrid sensor and regulator. | Bifunctional proline dehydrogenase/delta-1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family. | 0.446 |
cce_3118 | cce_3119 | cce_3118 | cce_3119 | D-alanine--D-alanine ligase. | Na+/solute symporter; Catalyzes the sodium-dependent uptake of extracellular L- proline; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. | 0.592 |
cce_3118 | cce_3120 | cce_3118 | cce_3120 | D-alanine--D-alanine ligase. | Conserved hypothetical protein. | 0.870 |
cce_3119 | acs | cce_3119 | cce_2016 | Na+/solute symporter; Catalyzes the sodium-dependent uptake of extracellular L- proline; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.533 |
cce_3119 | apt | cce_3119 | cce_2298 | Na+/solute symporter; Catalyzes the sodium-dependent uptake of extracellular L- proline; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.641 |
cce_3119 | cce_0329 | cce_3119 | cce_0329 | Na+/solute symporter; Catalyzes the sodium-dependent uptake of extracellular L- proline; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. | Probable sodium-dependent transporter. | 0.481 |
cce_3119 | cce_0863 | cce_3119 | cce_0863 | Na+/solute symporter; Catalyzes the sodium-dependent uptake of extracellular L- proline; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. | Na+/alanine symporter. | 0.721 |
cce_3119 | cce_0948 | cce_3119 | cce_0948 | Na+/solute symporter; Catalyzes the sodium-dependent uptake of extracellular L- proline; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. | ATP-binding protein of amino acid ABC transporter. | 0.611 |