| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| adk | cce_5005 | cce_4034 | cce_5005 | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | Hypothetical protein; Contains Helicase, C-terminal, Type III restriction enzyme, res subunit and DEAD/DEAH box helicase, N-terminal domains. | 0.640 |
| adk | gyrB | cce_4034 | cce_0758 | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | DNA gyrase B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.415 |
| adk | ksgA | cce_4034 | cce_2498 | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | rRNA dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | 0.411 |
| adk | smc | cce_4034 | cce_3297 | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | Chromosome segregation protein SMC; Required for chromosome condensation and partitioning. Belongs to the SMC family. | 0.474 |
| cce_0335 | cce_0429 | cce_0335 | cce_0429 | Putative Prokaryotic chromosome segregation and condensation protein ScpA; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves. | Putative prokaryotic chromosome segregation and condensation protein ScpB; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves. | 0.994 |
| cce_0335 | sepF | cce_0335 | cce_2614 | Putative Prokaryotic chromosome segregation and condensation protein ScpA; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves. | Unknown; Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA. | 0.422 |
| cce_0335 | smc | cce_0335 | cce_3297 | Putative Prokaryotic chromosome segregation and condensation protein ScpA; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves. | Chromosome segregation protein SMC; Required for chromosome condensation and partitioning. Belongs to the SMC family. | 0.880 |
| cce_0429 | cce_0335 | cce_0429 | cce_0335 | Putative prokaryotic chromosome segregation and condensation protein ScpB; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves. | Putative Prokaryotic chromosome segregation and condensation protein ScpA; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves. | 0.994 |
| cce_0429 | ksgA | cce_0429 | cce_2498 | Putative prokaryotic chromosome segregation and condensation protein ScpB; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves. | rRNA dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | 0.538 |
| cce_0429 | smc | cce_0429 | cce_3297 | Putative prokaryotic chromosome segregation and condensation protein ScpB; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves. | Chromosome segregation protein SMC; Required for chromosome condensation and partitioning. Belongs to the SMC family. | 0.747 |
| cce_3296 | cce_5005 | cce_3296 | cce_5005 | Hypothetical protein; Contains DUF29. | Hypothetical protein; Contains Helicase, C-terminal, Type III restriction enzyme, res subunit and DEAD/DEAH box helicase, N-terminal domains. | 0.791 |
| cce_3296 | smc | cce_3296 | cce_3297 | Hypothetical protein; Contains DUF29. | Chromosome segregation protein SMC; Required for chromosome condensation and partitioning. Belongs to the SMC family. | 0.487 |
| cce_5005 | adk | cce_5005 | cce_4034 | Hypothetical protein; Contains Helicase, C-terminal, Type III restriction enzyme, res subunit and DEAD/DEAH box helicase, N-terminal domains. | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | 0.640 |
| cce_5005 | cce_3296 | cce_5005 | cce_3296 | Hypothetical protein; Contains Helicase, C-terminal, Type III restriction enzyme, res subunit and DEAD/DEAH box helicase, N-terminal domains. | Hypothetical protein; Contains DUF29. | 0.791 |
| cce_5005 | gyrB | cce_5005 | cce_0758 | Hypothetical protein; Contains Helicase, C-terminal, Type III restriction enzyme, res subunit and DEAD/DEAH box helicase, N-terminal domains. | DNA gyrase B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.910 |
| cce_5005 | smc | cce_5005 | cce_3297 | Hypothetical protein; Contains Helicase, C-terminal, Type III restriction enzyme, res subunit and DEAD/DEAH box helicase, N-terminal domains. | Chromosome segregation protein SMC; Required for chromosome condensation and partitioning. Belongs to the SMC family. | 0.536 |
| cce_5005 | topA1 | cce_5005 | cce_1235 | Hypothetical protein; Contains Helicase, C-terminal, Type III restriction enzyme, res subunit and DEAD/DEAH box helicase, N-terminal domains. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.820 |
| gidB | smc | cce_3918 | cce_3297 | Glucose inhibited division protein B; Specifically methylates the N7 position of a guanine in 16S rRNA; Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family. | Chromosome segregation protein SMC; Required for chromosome condensation and partitioning. Belongs to the SMC family. | 0.545 |
| gyrB | adk | cce_0758 | cce_4034 | DNA gyrase B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | 0.415 |
| gyrB | cce_5005 | cce_0758 | cce_5005 | DNA gyrase B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | Hypothetical protein; Contains Helicase, C-terminal, Type III restriction enzyme, res subunit and DEAD/DEAH box helicase, N-terminal domains. | 0.910 |