Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
cce_3375Transcriptional regulator. (197 aa)    
Predicted Functional Partners:
cce_3078
Polyketide synthase.
   
 
 0.625
cce_2192
Putative HlyD-family secretion protein.
 
   
 0.575
pth
peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family.
  
    0.571
rimI
Ribosomal-protein-alanine acetyltransferase.
     
 0.567
cce_3077
AMP-dependent synthetase and ligase, probable acyl-CoA synthase.
 
   
 0.530
cce_3494
Glycerophosphoryl diester phosphodiesterase; Belongs to the alkaline phosphatase family.
  
   
 0.497
cce_3079
Probable polyketide synthase.
     
 0.473
guaA
GMP synthetase; Catalyzes the synthesis of GMP from XMP.
     
 0.473
cce_1185
Two-component hybrid sensor and regulator.
    
 
 0.466
cce_1521
Unknown; Contains PAS, GGDEF, EAL, Response regulator receiver, CheY-like, and PAS fold-3 domains.
   
 
 0.432
Your Current Organism:
Crocosphaera subtropica
NCBI taxonomy Id: 43989
Other names: C. subtropica ATCC 51142, Crocosphaera subtropica ATCC 51142, Cyanothece sp. ATCC 51142, Cyanothece sp. BH68, Cyanothece sp. BH68K
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