Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
cce_3558Two-component hybrid sensor and regulator. (1680 aa)    
Predicted Functional Partners:
cce_1185
Two-component hybrid sensor and regulator.
 
 
0.983
cce_1777
Probable two-component hybrid sensor and regulator.
 
 
0.980
cce_3559
Two-component response regulator.
 
 
 0.976
cce_1186
Two-component hybrid sensor and regulator.
 
 
0.951
cce_0970
Two-component transcription regulator.
 
 
 0.926
cce_3557
Two-component response regulator.
 
 
 0.922
cce_0164
Two-component sensor histidine kinase.
 
 
0.914
cce_4289
Two-component hybrid sensor and regulator.
 
 
0.914
cce_4728
Adenylyl/guanylyl cyclase.
 
 
 0.907
cce_4709
Unknown; Contains a GGDEF domain, EAL domain, and PAS fold-3 domain.
  
 
 0.896
Your Current Organism:
Crocosphaera subtropica
NCBI taxonomy Id: 43989
Other names: C. subtropica ATCC 51142, Crocosphaera subtropica ATCC 51142, Cyanothece sp. ATCC 51142, Cyanothece sp. BH68, Cyanothece sp. BH68K
Server load: low (18%) [HD]