STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cce_4391Probable guanosine-3',5'-bis(diphosphate) 3'-diphosphatase, (ppGpp)ase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (744 aa)    
Predicted Functional Partners:
rps6
30s ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA.
  
 
 0.940
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
  
 
 0.925
ppx
Exopolyphosphatase.
  
 
 0.923
pykF1
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 
 0.922
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
    
 0.920
cce_4728
Adenylyl/guanylyl cyclase.
  
 
 0.917
pykF4
Pyruvate kinase; Belongs to the pyruvate kinase family.
   
 
 0.901
pykF3
Pyruvate kinase; Belongs to the pyruvate kinase family.
   
 
 0.901
pykF2
Pyruvate kinase; Belongs to the pyruvate kinase family.
   
 
 0.901
cce_0530
Putative adenylate cyclase.
     
  0.900
Your Current Organism:
Crocosphaera subtropica
NCBI taxonomy Id: 43989
Other names: C. subtropica ATCC 51142, Crocosphaera subtropica ATCC 51142, Cyanothece sp. ATCC 51142, Cyanothece sp. BH68, Cyanothece sp. BH68K
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