Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
manA2Mannose-6-phosphate isomerase. (122 aa)    
Predicted Functional Partners:
manC
Mannose-1-phosphate guanylyltransferase.
     0.969
cce_2061
Mannose-1-phosphate guanyltransferase.
  
 
 0.935
glmS
Glucosamine-fructose-6-phosphate aminotransferase, isomerising; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
    
 0.910
pgi1
Glucose-6-phosphate isomerase; Belongs to the GPI family.
    
 0.907
fbp
Fructose 1,6-bisphosphatase I.
    
  0.907
pgi2
Glucose-6-phosphate isomerase; Belongs to the GPI family.
    
 0.907
manA1
Mannose-6-phosphate isomerase.
  
  
 
0.903
nagB
glucosamine-6-P isomerase.
     
 0.901
pfkA1
6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
     
  0.900
pfkA2
6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family.
     
  0.900
Your Current Organism:
Crocosphaera subtropica
NCBI taxonomy Id: 43989
Other names: C. subtropica ATCC 51142, Crocosphaera subtropica ATCC 51142, Cyanothece sp. ATCC 51142, Cyanothece sp. BH68, Cyanothece sp. BH68K
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