Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
shcSqualene-hopene-cyclase. (663 aa)    
Predicted Functional Partners:
cce_1843
Putative terpenoid synthase.
 
 
 0.987
cce_2500
Hypothetical protein; Contains a radical SAM domain.
   
 0.935
dfrA
Probable dihydrokaempferol 4-reductase.
 
 
 0.823
cce_3629
Unknown; Contains a glycosyl transferase, family 2 domain.
 
     0.793
cce_3800
Hypothetical protein; Contains a purine and other phosphorylases, family 1 domain.
 
   
 0.792
cce_4095
Unknown; Contains UPF0004.
 
   
 0.712
cce_0675
Sterol desaturase family protein.
   
 
 0.626
cce_3041
Conserved hypothetical protein.
   
 
 0.626
cce_0751
Hypothetical protein; Contains a glycosyl transferase, family 2 domain.
 
     0.623
ispH
Putative LytB protein; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family.
     
 0.591
Your Current Organism:
Crocosphaera subtropica
NCBI taxonomy Id: 43989
Other names: C. subtropica ATCC 51142, Crocosphaera subtropica ATCC 51142, Cyanothece sp. ATCC 51142, Cyanothece sp. BH68, Cyanothece sp. BH68K
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.