| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| cce_1075 | cce_1788 | cce_1075 | cce_1788 | Hypothetical protein; Contains a WD-40 repeat and peptidase C14, caspase catalytic subunit p20 domain. | ATP-requiring DNA helicase. | 0.651 |
| cce_1075 | polA | cce_1075 | cce_2255 | Hypothetical protein; Contains a WD-40 repeat and peptidase C14, caspase catalytic subunit p20 domain. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.930 |
| cce_1075 | recA | cce_1075 | cce_4639 | Hypothetical protein; Contains a WD-40 repeat and peptidase C14, caspase catalytic subunit p20 domain. | Recombination protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.932 |
| cce_1075 | recQ | cce_1075 | cce_2137 | Hypothetical protein; Contains a WD-40 repeat and peptidase C14, caspase catalytic subunit p20 domain. | ATP-dependent DNA helicase. | 0.651 |
| cce_1075 | topA1 | cce_1075 | cce_1235 | Hypothetical protein; Contains a WD-40 repeat and peptidase C14, caspase catalytic subunit p20 domain. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.540 |
| cce_1788 | cce_1075 | cce_1788 | cce_1075 | ATP-requiring DNA helicase. | Hypothetical protein; Contains a WD-40 repeat and peptidase C14, caspase catalytic subunit p20 domain. | 0.651 |
| cce_1788 | polA | cce_1788 | cce_2255 | ATP-requiring DNA helicase. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.944 |
| cce_1788 | radA | cce_1788 | cce_4001 | ATP-requiring DNA helicase. | DNA repair protein radA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. | 0.514 |
| cce_1788 | recA | cce_1788 | cce_4639 | ATP-requiring DNA helicase. | Recombination protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.897 |
| cce_1788 | recN | cce_1788 | cce_2438 | ATP-requiring DNA helicase. | DNA repair protein; May be involved in recombinational repair of damaged DNA. | 0.543 |
| cce_1788 | recQ | cce_1788 | cce_2137 | ATP-requiring DNA helicase. | ATP-dependent DNA helicase. | 0.919 |
| cce_1788 | topA1 | cce_1788 | cce_1235 | ATP-requiring DNA helicase. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.837 |
| cce_5074 | recA | cce_5074 | cce_4639 | LexA-like protein; Represses a number of genes involved in the response to DNA damage (SOS response). | Recombination protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.915 |
| cce_5074 | recN | cce_5074 | cce_2438 | LexA-like protein; Represses a number of genes involved in the response to DNA damage (SOS response). | DNA repair protein; May be involved in recombinational repair of damaged DNA. | 0.555 |
| lexA | polA | cce_1899 | cce_2255 | SOS function regulatory protein; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.479 |
| lexA | radA | cce_1899 | cce_4001 | SOS function regulatory protein; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. | DNA repair protein radA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. | 0.728 |
| lexA | recA | cce_1899 | cce_4639 | SOS function regulatory protein; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. | Recombination protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.970 |
| lexA | recN | cce_1899 | cce_2438 | SOS function regulatory protein; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. | DNA repair protein; May be involved in recombinational repair of damaged DNA. | 0.843 |
| lexA | recQ | cce_1899 | cce_2137 | SOS function regulatory protein; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. | ATP-dependent DNA helicase. | 0.724 |
| lexA | uvrA | cce_1899 | cce_3691 | SOS function regulatory protein; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. | Excinuclease ABC subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. | 0.786 |
