| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| cbiA | cbiB | cce_4641 | cce_0450 | Cobyrinic acid ac-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Cobalamin biosynthetic protein; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | 0.894 |
| cbiA | cbiC2 | cce_4641 | cce_1970 | Cobyrinic acid ac-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | precorrin-8X methylmutase. | 0.991 |
| cbiA | cbiGH | cce_4641 | cce_0926 | Cobyrinic acid ac-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Probable bifunctional Cobalamin (vitamin B12) biosynthesis/precorrin-3B C17-methyltransferase. | 0.969 |
| cbiA | cce_1085 | cce_4641 | cce_1085 | Cobyrinic acid ac-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Hypothetical protein; Contains DUF102; Belongs to the UPF0284 family. | 0.590 |
| cbiA | cobM | cce_4641 | cce_1618 | Cobyrinic acid ac-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Precorrin-4 C11-methyltransferase; Belongs to the precorrin methyltransferase family. | 0.901 |
| cbiA | cobO | cce_4641 | cce_0802 | Cobyrinic acid ac-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | cob(I)alamin adenosyltransferase. | 0.982 |
| cbiA | cobQ | cce_4641 | cce_3359 | Cobyrinic acid ac-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.986 |
| cbiA | cobS | cce_4641 | cce_1645 | Cobyrinic acid ac-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Putative cobalamin-5-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | 0.852 |
| cbiA | cobU | cce_4641 | cce_4757 | Cobyrinic acid ac-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Bifunctional cobalbumin biosynthesis enzyme. | 0.942 |
| cbiB | cbiA | cce_0450 | cce_4641 | Cobalamin biosynthetic protein; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | Cobyrinic acid ac-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | 0.894 |
| cbiB | cbiC2 | cce_0450 | cce_1970 | Cobalamin biosynthetic protein; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | precorrin-8X methylmutase. | 0.887 |
| cbiB | cbiGH | cce_0450 | cce_0926 | Cobalamin biosynthetic protein; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | Probable bifunctional Cobalamin (vitamin B12) biosynthesis/precorrin-3B C17-methyltransferase. | 0.902 |
| cbiB | cce_1085 | cce_0450 | cce_1085 | Cobalamin biosynthetic protein; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | Hypothetical protein; Contains DUF102; Belongs to the UPF0284 family. | 0.400 |
| cbiB | cobM | cce_0450 | cce_1618 | Cobalamin biosynthetic protein; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | Precorrin-4 C11-methyltransferase; Belongs to the precorrin methyltransferase family. | 0.859 |
| cbiB | cobO | cce_0450 | cce_0802 | Cobalamin biosynthetic protein; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | cob(I)alamin adenosyltransferase. | 0.979 |
| cbiB | cobQ | cce_0450 | cce_3359 | Cobalamin biosynthetic protein; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.990 |
| cbiB | cobS | cce_0450 | cce_1645 | Cobalamin biosynthetic protein; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | Putative cobalamin-5-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | 0.856 |
| cbiB | cobU | cce_0450 | cce_4757 | Cobalamin biosynthetic protein; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | Bifunctional cobalbumin biosynthesis enzyme. | 0.992 |
| cbiC2 | cbiA | cce_1970 | cce_4641 | precorrin-8X methylmutase. | Cobyrinic acid ac-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | 0.991 |
| cbiC2 | cbiB | cce_1970 | cce_0450 | precorrin-8X methylmutase. | Cobalamin biosynthetic protein; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | 0.887 |