| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| cce_1788 | cce_5005 | cce_1788 | cce_5005 | ATP-requiring DNA helicase. | Hypothetical protein; Contains Helicase, C-terminal, Type III restriction enzyme, res subunit and DEAD/DEAH box helicase, N-terminal domains. | 0.874 |
| cce_1788 | polA | cce_1788 | cce_2255 | ATP-requiring DNA helicase. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.944 |
| cce_1788 | recA | cce_1788 | cce_4639 | ATP-requiring DNA helicase. | Recombination protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.897 |
| cce_1788 | recQ | cce_1788 | cce_2137 | ATP-requiring DNA helicase. | ATP-dependent DNA helicase. | 0.919 |
| cce_1788 | topA2 | cce_1788 | cce_4808 | ATP-requiring DNA helicase. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.794 |
| cce_4807 | topA2 | cce_4807 | cce_4808 | Hypothetical protein. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.714 |
| cce_5005 | cce_1788 | cce_5005 | cce_1788 | Hypothetical protein; Contains Helicase, C-terminal, Type III restriction enzyme, res subunit and DEAD/DEAH box helicase, N-terminal domains. | ATP-requiring DNA helicase. | 0.874 |
| cce_5005 | polA | cce_5005 | cce_2255 | Hypothetical protein; Contains Helicase, C-terminal, Type III restriction enzyme, res subunit and DEAD/DEAH box helicase, N-terminal domains. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.958 |
| cce_5005 | recA | cce_5005 | cce_4639 | Hypothetical protein; Contains Helicase, C-terminal, Type III restriction enzyme, res subunit and DEAD/DEAH box helicase, N-terminal domains. | Recombination protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.853 |
| cce_5005 | recQ | cce_5005 | cce_2137 | Hypothetical protein; Contains Helicase, C-terminal, Type III restriction enzyme, res subunit and DEAD/DEAH box helicase, N-terminal domains. | ATP-dependent DNA helicase. | 0.874 |
| cce_5005 | topA2 | cce_5005 | cce_4808 | Hypothetical protein; Contains Helicase, C-terminal, Type III restriction enzyme, res subunit and DEAD/DEAH box helicase, N-terminal domains. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.743 |
| ccs1 | murB | cce_4132 | cce_2372 | C-type cytochrome biogenesis protein; Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment. | UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. | 0.723 |
| ccs1 | murG | cce_4132 | cce_1284 | C-type cytochrome biogenesis protein; Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment. | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.725 |
| ccs1 | topA2 | cce_4132 | cce_4808 | C-type cytochrome biogenesis protein; Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.693 |
| murB | ccs1 | cce_2372 | cce_4132 | UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. | C-type cytochrome biogenesis protein; Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment. | 0.723 |
| murB | murG | cce_2372 | cce_1284 | UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.959 |
| murB | topA2 | cce_2372 | cce_4808 | UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.700 |
| murG | ccs1 | cce_1284 | cce_4132 | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | C-type cytochrome biogenesis protein; Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment. | 0.725 |
| murG | murB | cce_1284 | cce_2372 | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. | 0.959 |
| murG | topA2 | cce_1284 | cce_4808 | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.713 |
