| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| cbiA | cbiGH | cce_4641 | cce_0926 | Cobyrinic acid ac-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Probable bifunctional Cobalamin (vitamin B12) biosynthesis/precorrin-3B C17-methyltransferase. | 0.976 |
| cbiA | cce_4902 | cce_4641 | cce_4902 | Cobyrinic acid ac-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Putative substrate-binding protein of ABC transporter. | 0.902 |
| cbiA | hemD | cce_4641 | cce_2117 | Cobyrinic acid ac-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Bifunctional uroporphyrin-III C-methyltransferase/uroporphyrinogen-III synthase; Belongs to the precorrin methyltransferase family. | 0.715 |
| cbiA | metH | cce_4641 | cce_0077 | Cobyrinic acid ac-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.480 |
| cbiGH | cbiA | cce_0926 | cce_4641 | Probable bifunctional Cobalamin (vitamin B12) biosynthesis/precorrin-3B C17-methyltransferase. | Cobyrinic acid ac-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | 0.976 |
| cbiGH | cce_4902 | cce_0926 | cce_4902 | Probable bifunctional Cobalamin (vitamin B12) biosynthesis/precorrin-3B C17-methyltransferase. | Putative substrate-binding protein of ABC transporter. | 0.512 |
| cbiGH | hemD | cce_0926 | cce_2117 | Probable bifunctional Cobalamin (vitamin B12) biosynthesis/precorrin-3B C17-methyltransferase. | Bifunctional uroporphyrin-III C-methyltransferase/uroporphyrinogen-III synthase; Belongs to the precorrin methyltransferase family. | 0.776 |
| cbiGH | metH | cce_0926 | cce_0077 | Probable bifunctional Cobalamin (vitamin B12) biosynthesis/precorrin-3B C17-methyltransferase. | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.552 |
| cce_3078 | cce_3079 | cce_3078 | cce_3079 | Polyketide synthase. | Probable polyketide synthase. | 0.998 |
| cce_3078 | cce_4901 | cce_3078 | cce_4901 | Polyketide synthase. | Probable short-chain dehydrogenase/reductase SDR; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 0.555 |
| cce_3078 | cce_4902 | cce_3078 | cce_4902 | Polyketide synthase. | Putative substrate-binding protein of ABC transporter. | 0.653 |
| cce_3078 | coaE | cce_3078 | cce_3740 | Polyketide synthase. | Putative Dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.631 |
| cce_3078 | metH | cce_3078 | cce_0077 | Polyketide synthase. | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.666 |
| cce_3079 | cce_3078 | cce_3079 | cce_3078 | Probable polyketide synthase. | Polyketide synthase. | 0.998 |
| cce_3079 | cce_4901 | cce_3079 | cce_4901 | Probable polyketide synthase. | Probable short-chain dehydrogenase/reductase SDR; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 0.538 |
| cce_3079 | cce_4902 | cce_3079 | cce_4902 | Probable polyketide synthase. | Putative substrate-binding protein of ABC transporter. | 0.562 |
| cce_3079 | coaE | cce_3079 | cce_3740 | Probable polyketide synthase. | Putative Dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.623 |
| cce_3079 | metH | cce_3079 | cce_0077 | Probable polyketide synthase. | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.509 |
| cce_4901 | cce_3078 | cce_4901 | cce_3078 | Probable short-chain dehydrogenase/reductase SDR; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | Polyketide synthase. | 0.555 |
| cce_4901 | cce_3079 | cce_4901 | cce_3079 | Probable short-chain dehydrogenase/reductase SDR; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | Probable polyketide synthase. | 0.538 |