Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
pepTPeptidase T; Cleaves the N-terminal amino acid of tripeptides. Belongs to the peptidase M20B family. (411 aa)    
Predicted Functional Partners:
OJG40210.1
YbgI/family dinuclear metal center protein; Belongs to the GTP cyclohydrolase I type 2/NIF3 family.
  
    0.860
mprF
Hypothetical protein; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms.
     
 0.715
OJG40211.1
Hypothetical protein.
  
    0.705
OJG40208.1
Hypothetical protein.
       0.703
OJG40212.1
Primosomal protein DnaI.
       0.641
OJG40213.1
Hypothetical protein.
       0.641
nrdR
Transcriptional repressor NrdR; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family.
       0.634
OJG38736.1
xaa-Pro dipeptidase.
  
 
 0.554
OJG38363.1
xaa-Pro dipeptidase; Belongs to the peptidase M24B family.
  
 
 0.554
OJG39741.1
Tyrosine decarboxylase.
      
 0.533
Your Current Organism:
Enterococcus dispar
NCBI taxonomy Id: 44009
Other names: ATCC 51266, CCUG 33309, CIP 103646, DSM 6630, E. dispar, HAMBI 2231, LMG 13521, LMG:13521, NBRC 100678, NCFB 2821, NCIMB 13000, strain E18-1
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