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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
OJG37897.1hydroxymethylglutaryl-CoA synthase. (383 aa)    
Predicted Functional Partners:
OJG37896.1
hydroxymethylglutaryl-CoA reductase, degradative.
 0.999
OJG38551.1
Diphosphomevalonate decarboxylase.
 
 
 0.958
OJG38550.1
Mevalonate kinase.
 
  
 0.918
OJG38041.1
Pyruvate:ferredoxin (flavodoxin) oxidoreductase.
     
 0.914
OJG38552.1
Phosphomevalonate kinase.
 
  
 0.911
OJG36207.1
Formate acetyltransferase.
    
  0.900
OJG38729.1
Hypothetical protein; Belongs to the citrate synthase family.
    
 0.881
fni
Isopentenyl-diphosphate delta-isomerase, type 2; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
 
  
 0.868
OJG40242.1
Dihydrolipoamide S-succinyltransferase.
   
 
 0.818
OJG37957.1
Beta-ketoacyl-acyl-carrier-protein synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.
  
 
 0.704
Your Current Organism:
Enterococcus dispar
NCBI taxonomy Id: 44009
Other names: ATCC 51266, CCUG 33309, CIP 103646, DSM 6630, E. dispar, HAMBI 2231, LMG 13521, LMG:13521, NBRC 100678, NCFB 2821, NCIMB 13000, strain E18-1
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