Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ORV46758.1FAD-binding monooxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (513 aa)    
Predicted Functional Partners:
ORV46756.1
Extradiol ring-cleavage dioxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.967
ORV46757.1
2-hydroxy-6-ketonona-2,4-dienedioic acid hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  0.929
ORV46755.1
Amidohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.923
mhpB
3-(2,3-dihydroxyphenyl)propionate dioxygenase; Catalyzes the non-heme iron(II)-dependent oxidative cleavage of 2,3-dihydroxyphenylpropionic acid and 2,3-dihydroxicinnamic acid into 2-hydroxy-6-ketononadienedioate and 2-hydroxy-6- ketononatrienedioate, respectively; Belongs to the LigB/MhpB extradiol dioxygenase family.
 
  
 0.872
mhpA
3-(3-hydroxyphenyl)propionate hydroxylase; Catalyzes the insertion of one atom of molecular oxygen into position 2 of the phenyl ring of 3-(3-hydroxyphenyl)propionate (3-HPP) and hydroxycinnamic acid (3HCI).
  
  
 
0.871
ORV46759.1
TetR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.818
ORV45833.1
2,3-dihydroxy-2,3-dihydrophenylpropionate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.617
ORV47106.1
Short-chain dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.548
ORV44013.1
(2Fe-2S)-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
  0.506
ORV40490.1
Polyketide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.505
Your Current Organism:
Mycobacterium conspicuum
NCBI taxonomy Id: 44010
Other names: ATCC 700090, CIP 105165, DSM 44136, JCM 14738, M. conspicuum, strain 3895/92
Server load: low (18%) [HD]