STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ORV42365.1Hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (518 aa)    
Predicted Functional Partners:
ORV40490.1
Polyketide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.820
ORV42597.1
Polyketide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.820
ORV41575.1
Polyketide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.820
ORV40071.1
Polyketide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.820
ORV36772.1
Polyketide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.820
ORV42363.1
Glutamine synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutamine synthetase family.
       0.712
glnE
Glutamine-synthetase adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transducti [...]
     
 0.701
ORV44813.1
acyl-CoA synthetase; Activates fatty acids by binding to coenzyme A; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.681
ORV41757.1
3-oxoacyl-ACP synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.658
ORV39154.1
Polyketide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.635
Your Current Organism:
Mycobacterium conspicuum
NCBI taxonomy Id: 44010
Other names: ATCC 700090, CIP 105165, DSM 44136, JCM 14738, M. conspicuum, strain 3895/92
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