STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SDG74175.1Nuclease homologue. (178 aa)    
Predicted Functional Partners:
guaA
GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP.
    
  0.746
guaB
IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
 0.735
rnpA
Ribonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
   
    0.629
SDG74163.1
Succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
   
   0.573
SDG51755.1
Thiosulfate reductase cytochrome b subunit.
  
     0.497
lptD
LPS-assembly protein; Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane; Belongs to the LptD family.
  
     0.467
SDG71347.1
Outer membrane protein (porin).
  
     0.440
tdk
Thymidine kinase.
  
  
  0.425
Your Current Organism:
Pelagibacterium luteolum
NCBI taxonomy Id: 440168
Other names: CELMS EEUT 1C1627, CGMCC 1.10267, Devosia sp. 1_C16_27, Hyphomicrobiaceae bacterium 1_C16_27, JCM 16552, P. luteolum, Pelagibacterium luteolum Xu et al. 2011, strain 1_C16_27
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.