Genes that are sometimes fused into single open reading frames.
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Experiments
Co-purification, co-crystallization, Yeast2Hybrid, Genetic Interactions, etc ... as imported from primary sources.
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Coexpression
Proteins whose genes are observed to be correlated in expression, across a large number of experiments.
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Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes: query proteins and first shell of interactors
white nodes: second shell of interactors
Node Content
empty nodes: proteins of unknown 3D structure
filled nodes: a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GCA_000718985_01746
Unannotated protein. (280 aa)
Predicted Functional Partners:
GCA_000718985_03913
Unannotated protein.
0.487
GCA_000718985_01745
Unannotated protein.
0.405
Your Current Organism:
Streptomyces megasporus
NCBI taxonomy Id: 44060 Other names: ATCC 43688, Actinomyces megasporus, DSM 41476, HUT 6610, IFO 14749, INA M-22, INMI 2869, JCM 6926, NBRC 14749, NRRL B-16372, S. megasporus, Streptomyces megalosporus