STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
acsE5-methyltetrahydrofolate:corrinoid/iron-sulfur protein co-methyltransferase. (358 aa)    
Predicted Functional Partners:
metH_2
Methionine synthase.
 
 0.998
CUH77651.1
Hypothetical protein.
 
 
 0.996
metH_1
Methionine synthase.
 
 0.995
metF
5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.
 
 
 0.973
CUH77649.1
Hypothetical protein.
 
     0.958
hom
Homoserine dehydrogenase.
  
 
 0.927
ahcY
Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
    
 0.915
fhs
Formate--tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family.
    
 0.914
metK
S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
    
 0.911
mdeA
Methionine gamma-lyase.
  
 
 0.904
Your Current Organism:
Tropicibacter naphthalenivorans
NCBI taxonomy Id: 441103
Other names: DSM 19561, JCM 14838, T. naphthalenivorans, Tropicibacter naphthalenivorans Harwati et al. 2009, alpha proteobacterium C02, strain C02
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