STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tesE2-hydroxyhexa-2,4-dienoate hydratase. (267 aa)    
Predicted Functional Partners:
hpcH
4-hydroxy-2-oxo-heptane-1,7-dioate aldolase; Belongs to the HpcH/HpaI aldolase family.
 
 0.995
hpcB
3,4-dihydroxyphenylacetate 2,3-dioxygenase.
 
  
 0.954
hpcD
5-carboxymethyl-2-hydroxymuconate Delta-isomerase.
 
 
 0.952
hpcE
Homoprotocatechuate catabolism bifunctional isomerase/decarboxylase.
 
 
 0.916
bphC_2
Manganese-dependent 2,3-dihydroxybiphenyl 1,2-dioxygenase.
   
 0.879
amnC_2
2-aminomuconic 6-semialdehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
 
  
 0.771
leuA_2
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
  
 
 0.759
gabD_2
Succinate-semialdehyde dehydrogenase [NADP(+)] GabD; Belongs to the aldehyde dehydrogenase family.
  
  
 0.755
CUH76337.1
Ureidoglycolate lyase.
 
 
 0.617
ohrR_2
Organic hydroperoxide resistance transcriptional regulator.
  
     0.600
Your Current Organism:
Tropicibacter naphthalenivorans
NCBI taxonomy Id: 441103
Other names: DSM 19561, JCM 14838, T. naphthalenivorans, Tropicibacter naphthalenivorans Harwati et al. 2009, alpha proteobacterium C02, strain C02
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