STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CMU_042520SWIB/MDM2 domain-containing protein. (435 aa)    
Predicted Functional Partners:
CMU_013060
SWIRM domain-containing protein.
    
 0.999
CMU_033820
ARID/BRIGHT DNA binding domain-containing protein.
   
 0.984
CMU_026180
Actin family protein; Belongs to the actin family.
   
 0.959
CMU_029250
Actin family protein; Belongs to the actin family.
   
 0.959
CMU_026280
Transcription regulatory protein SNF2, putative.
   
 0.950
CMU_003700
SNF2 family helicase, putative.
   
 0.950
CMU_011760
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
 0.918
CMU_016480
Centromere protein A, putative.
   
 0.813
CMU_018360
Histone H3; Belongs to the histone H3 family.
   
 0.813
CMU_000890
Histone H3; Belongs to the histone H3 family.
   
 0.813
Your Current Organism:
Cryptosporidium muris
NCBI taxonomy Id: 441375
Other names: C. muris RN66, Cryptosporidium muris RN66
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.