Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ACL_0010Two-component system response regulator with the CheY-like receiver domain. (216 aa)    
Predicted Functional Partners:
ACL_0011
Two-component sensory histidine kinase; This protein contains one predicted N-terminal transmembrane helix.
 
 0.998
ACL_1297
Two-component system, OmpR family, sensor histidine kinase; This protein contains three predicted N-terminal transmembrane helices.
 
 
 0.942
rpoD
DNA-directed RNA polymerase subunit D; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
   
 
 0.826
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.818
rpoB
DNA-directed RNA polymerase, subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.811
rpoC
DNA-directed RNA polymerase, subunit beta-prime; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.811
rpoZ
DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
   
 
 0.792
ACL_0190
Hypothetical surface-anchored protein; This protein contains one predicted N-terminal transmembrane helix.
  
  
 0.598
ACL_1328
Putative signalling protein.
 
 
 0.511
serS
seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec).
  
  
 0.499
Your Current Organism:
Acholeplasma laidlawii
NCBI taxonomy Id: 441768
Other names: A. laidlawii PG-8A, Acholeplasma laidlawii PG-8A, Acholeplasma laidlawii str. PG-8A, Acholeplasma laidlawii strain PG-8A
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