ACL_1069 protein (Acholeplasma laidlawii) - STRING interaction network

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Score

ACL_1069

REP family DNA helicase. (713 aa)

Predicted Functional Partners:

uvrD

0.925

ACL_1349

0.923

recA

0.848

uvrB

0.827

mutL

0.687

polA

0.653

ACL_1118

0.629

ACL_1409

0.613

ligA

0.608

ACL_0140

0.598

Your Current Organism:

Acholeplasma laidlawii

NCBI taxonomy Id: 441768
Other names: A. laidlawii PG-8A, Acholeplasma laidlawii PG-8A, Acholeplasma laidlawii str. PG-8A, Acholeplasma laidlawii strain PG-8A

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACL_0140	ACL_1069	ACL_0140	ACL_1069	Hypothetical surface-anchored protein; This protein contains one predicted N-terminal transmembrane domain.	REP family DNA helicase.	0.598
ACL_0140	ACL_1118	ACL_0140	ACL_1118	Hypothetical surface-anchored protein; This protein contains one predicted N-terminal transmembrane domain.	Large hypothetical surface-anchored protein; This protein contains one predicted N-terminal transmembrane helix, and one C-terminal transmembrane helix with the extracellular loop in the middle.	0.804
ACL_0140	ACL_1409	ACL_0140	ACL_1409	Hypothetical surface-anchored protein; This protein contains one predicted N-terminal transmembrane domain.	Hypothetical surface-anchored protein; This protein contains one predicted N-terminal transmembrane helix.	0.774
ACL_1069	ACL_0140	ACL_1069	ACL_0140	REP family DNA helicase.	Hypothetical surface-anchored protein; This protein contains one predicted N-terminal transmembrane domain.	0.598
ACL_1069	ACL_1118	ACL_1069	ACL_1118	REP family DNA helicase.	Large hypothetical surface-anchored protein; This protein contains one predicted N-terminal transmembrane helix, and one C-terminal transmembrane helix with the extracellular loop in the middle.	0.629
ACL_1069	ACL_1349	ACL_1069	ACL_1349	REP family DNA helicase.	DNA helicase, UvrD/REP type.	0.923
ACL_1069	ACL_1409	ACL_1069	ACL_1409	REP family DNA helicase.	Hypothetical surface-anchored protein; This protein contains one predicted N-terminal transmembrane helix.	0.613
ACL_1069	ligA	ACL_1069	ACL_1348	REP family DNA helicase.	DNA ligase, NAD-dependent; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.	0.608
ACL_1069	mutL	ACL_1069	ACL_0882	REP family DNA helicase.	DNA mismatch repair protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.	0.687
ACL_1069	polA	ACL_1069	ACL_0350	REP family DNA helicase.	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	0.653
ACL_1069	recA	ACL_1069	ACL_0890	REP family DNA helicase.	Recombination protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.	0.848
ACL_1069	uvrB	ACL_1069	ACL_1023	REP family DNA helicase.	Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...]	0.827
ACL_1069	uvrD	ACL_1069	ACL_1351	REP family DNA helicase.	DNA helicase II.	0.925
ACL_1118	ACL_0140	ACL_1118	ACL_0140	Large hypothetical surface-anchored protein; This protein contains one predicted N-terminal transmembrane helix, and one C-terminal transmembrane helix with the extracellular loop in the middle.	Hypothetical surface-anchored protein; This protein contains one predicted N-terminal transmembrane domain.	0.804
ACL_1118	ACL_1069	ACL_1118	ACL_1069	Large hypothetical surface-anchored protein; This protein contains one predicted N-terminal transmembrane helix, and one C-terminal transmembrane helix with the extracellular loop in the middle.	REP family DNA helicase.	0.629
ACL_1118	ACL_1409	ACL_1118	ACL_1409	Large hypothetical surface-anchored protein; This protein contains one predicted N-terminal transmembrane helix, and one C-terminal transmembrane helix with the extracellular loop in the middle.	Hypothetical surface-anchored protein; This protein contains one predicted N-terminal transmembrane helix.	0.774
ACL_1349	ACL_1069	ACL_1349	ACL_1069	DNA helicase, UvrD/REP type.	REP family DNA helicase.	0.923
ACL_1349	ligA	ACL_1349	ACL_1348	DNA helicase, UvrD/REP type.	DNA ligase, NAD-dependent; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.	0.823
ACL_1349	mutL	ACL_1349	ACL_0882	DNA helicase, UvrD/REP type.	DNA mismatch repair protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.	0.687
ACL_1349	polA	ACL_1349	ACL_0350	DNA helicase, UvrD/REP type.	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	0.653