STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SCN2ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1886 aa)    
Predicted Functional Partners:
UNC79
Protein unc-79.
   
 0.995
N308_13247
Sodium channel subunit beta-2.
   
 0.852
WDR35
WD repeat-containing protein 35.
    
 0.737
IFT122
Intraflagellar transport protein 122.
   
 0.730
IFT140
Intraflagellar transport 140.
    
 0.720
WDR19
WD repeat-containing protein 19.
    
 0.720
CACNG1
Voltage-dependent calcium channel gamma-1 subunit; Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Regulates channel inactivation kinetics.
   
 0.693
CALM1
Calmodulin; Belongs to the calmodulin family.
    
 0.672
ENSSCUP00000012675
annotation not available
    
 0.672
ENSSCUP00000014495
annotation not available
    
 0.672
Your Current Organism:
Struthio camelus
NCBI taxonomy Id: 441894
Other names: S. camelus australis, Struthio camelus australis
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