STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ITCHItchy E3 ubiquitin protein ligase. (878 aa)    
Predicted Functional Partners:
N308_02498
Ubiquitin-40S ribosomal protein S27a.
    
 0.968
CFLAR
CASP8 and FADD-like apoptosis regulator; Belongs to the peptidase C14A family.
    
 0.956
WWP1
NEDD4-like E3 ubiquitin-protein ligase WWP1.
  
 
0.952
N308_04198
Polyubiquitin.
    
 0.948
TRAF6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
    
 0.939
NUMB
Protein numb.
    
 0.937
TXNIP
Thioredoxin interacting protein.
    
 
 0.935
UBE2L3
Ubiquitin-conjugating enzyme E2 L3; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.933
UBA52
Ubiquitin-60S ribosomal protein L40.
    
 0.927
WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2.
  
 
0.902
Your Current Organism:
Struthio camelus
NCBI taxonomy Id: 441894
Other names: S. camelus australis, Struthio camelus australis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.