STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EXO1Exonuclease 1. (752 aa)    
Predicted Functional Partners:
WRN
WRN RecQ like helicase.
  
 0.998
MSH2
DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).
   
 0.992
MLH1
DNA mismatch repair protein Mlh1.
   
 0.992
RECQL4
ATP-dependent DNA helicase Q4.
  
 0.991
MRE11
Double-strand break repair protein MRE11; Belongs to the MRE11/RAD32 family.
  
 0.990
RAD51
DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...]
  
 0.989
DNA2
DNA replication ATP-dependent helicase/nuclease DNA2.
   
 0.987
SLF1
Ankyrin repeat domain-containing protein 32.
   
 0.987
BLM
Uncharacterized protein.
  
 0.987
MSH6
DNA mismatch repair protein Msh6; Component of the post-replicative DNA mismatch repair system (MMR).
   
 0.980
Your Current Organism:
Struthio camelus
NCBI taxonomy Id: 441894
Other names: S. camelus australis, Struthio camelus australis
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.