STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TSTA_032390PHD transcription factor, putative. (945 aa)    
Predicted Functional Partners:
TSTA_094840
WD repeat protein.
    
 0.923
TSTA_035740
Histone-lysine N-methyltransferase, H3 lysine-4 specific; Catalytic component of the COMPASS (Set1C) complex that specifically mono-, di- and trimethylates histone H3 to form H3K4me1/2/3, which subsequently plays a role in telomere length maintenance and transcription elongation regulation.
   
 0.918
TSTA_104250
Histone-lysine N-methyltransferase (Bre2), putative.
  
 0.907
TSTA_020600
COMPASS complex subunit Sdc1, putative.
    
 0.878
TSTA_093550
WD repeat protein.
    
 0.873
TSTA_093380
WD repeat protein.
    
   0.856
TSTA_087070
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
  0.656
TSTA_048830
Peptidase family M20/M25/M40 protein.
   
 
 0.656
TSTA_103810
Histone H2A; Belongs to the histone H2A family.
    
   0.641
TSTA_050360
RSC complex subunit (RSC8), putative.
    
 
 0.623
Your Current Organism:
Talaromyces stipitatus
NCBI taxonomy Id: 441959
Other names: T. stipitatus ATCC 10500, Talaromyces stipitatus ATCC 10500
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.