STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
get3ATPase get3; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. S [...] (340 aa)    
Predicted Functional Partners:
get1
Protein get1; Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Acts as a membrane receptor for soluble get3, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol.
    
 0.995
TSTA_005510
DUF410 domain protein.
    
 0.990
TSTA_120220
UV excision repair protein (RadW), putative.
   
 0.969
TSTA_071120
Uncharacterized protein.
    
 0.964
TSTA_074170
Hsc70 cochaperone (SGT), putative.
   
 0.948
TSTA_123530
ER-Golgi SNARE complex subunit (Sed5), putative.
   
 0.880
TSTA_125750
Low molecular weight phosphotyrosine protein phosphatase, putative.
    
 0.868
TSTA_002880
Arsenate reductase (ArsC), putative.
    
 0.868
TSTA_018890
Translocon protein Sec61beta, putative.
    
 0.861
TSTA_077640
Uncharacterized protein.
    
 0.813
Your Current Organism:
Talaromyces stipitatus
NCBI taxonomy Id: 441959
Other names: T. stipitatus ATCC 10500, Talaromyces stipitatus ATCC 10500
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