STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
get3ATPase get3; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. S [...] (340 aa)    
Predicted Functional Partners:
get1
Protein get1; Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Acts as a membrane receptor for soluble get3, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol.
    
 0.995
PMAA_011610
DUF410 domain protein.
    
 0.994
PMAA_085050
UV excision repair protein (RadW), putative.
   
 0.937
PMAA_027610
Uncharacterized protein.
    
 0.905
PMAA_044460
Hsc70 cochaperone (SGT), putative.
   
 0.859
PMAA_088260
ER-Golgi SNARE complex subunit (Sed5), putative.
   
 0.789
PMAA_089720
Low molecular weight phosphotyrosine protein phosphatase, putative.
    
 0.780
PMAA_014230
Arsenate reductase (ArsC), putative.
    
 0.780
PMAA_034890
Zn(2)-C6 fungal-type domain-containing protein.
    
 0.665
PMAA_065870
Zn(2)-C6 fungal-type domain-containing protein.
    
 0.665
Your Current Organism:
Talaromyces marneffei
NCBI taxonomy Id: 441960
Other names: Penicillium marneffei ATCC 18224, T. marneffei ATCC 18224, Talaromyces marneffei ATCC 18224
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