STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SFI08385.1Phosphogluconate 2-dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (329 aa)    
Predicted Functional Partners:
SFI08371.1
2-dehydro-3-deoxygluconokinase.
 
 
  0.982
pgl
6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.
   
 0.927
gcvP
Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
     
 0.852
SFI08346.1
Xylose isomerase-like TIM barrel.
 
 
  0.831
SFI04699.1
Hydroxypyruvate reductase.
 
 0.828
SFH65332.1
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 0.797
SFH30771.1
6-phosphogluconate dehydrogenase.
    
 0.796
SFI08323.1
Transcriptional regulator, LacI family.
 
    0.793
SFH73741.1
Fumarase, class I, homodimeric; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
     
 0.779
SFH44850.1
Flagellar protein FlaG.
    
   0.745
Your Current Organism:
Halomonas xianhensis
NCBI taxonomy Id: 442341
Other names: CGMCC 1.6848, H. xianhensis, Halomonas sp. A-1, Halomonas xianhensis Zhao et al. 2012, JCM 14849, strain A-1
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