Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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textmining
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AIQ11125.1Epoxyqueuosine reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (394 aa)    
Predicted Functional Partners:
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
 
 
 
 0.787
queA
S-adenosylmethionine tRNA ribosyltransferase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
 
  
 0.728
AIQ11126.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.722
nnrD
Carbohydrate kinase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epim [...]
     
 0.721
folE
GTP cyclohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.719
AIQ11124.1
GCN5 family acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.683
AIQ10817.1
Cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
      0.653
AIQ13243.1
Pyruvate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.634
AIQ14309.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.595
AIQ13194.1
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
  
 0.583
Your Current Organism:
Paenibacillus durus
NCBI taxonomy Id: 44251
Other names: ATCC 27763, ATCC 35681 [[Paenibacillus azotofixans]], Bacillus azotifixans, Bacillus azotofixans, CIP 104586 [[Paenibacillus azotofixans]], Clostridium durum, DSM 5976 [[Paenibacillus azotofixans]], LMG 14658 [[Paenibacillus azotofixans]], LMG:14658 [[Paenibacillus azotofixans]], P. durus, Paenibacillus azotofixans, Paenibacillus durum, VPI 6563, bacterium ISSDS-862, strain P3L-5 [[Paenibacillus azotofixans]]
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