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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cobBSir2 family protein; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class U subfamily. (250 aa)    
Predicted Functional Partners:
DJ90_1306
Cyt_tran_rel: cytidyltransferase-like domain protein.
   
 
 0.997
deoD
deoD: purine nucleoside phosphorylase.
    
 0.918
nadD
Nicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
   
 0.905
nadE
NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family.
    
 0.901
nadK
ATP-NAD kinase family protein; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
  
 
 0.894
DJ90_3759
Inosine-uridine preferring nucleoside hydrolase family protein.
   
 
 0.860
DJ90_3553
Histone deacetylase domain protein.
    
 
 0.837
DJ90_5725
FAD binding domain protein.
  
 0.809
DJ90_2436
HAD-SF-IA-v1: HAD hydrolase, IA, variant 1 family protein.
       0.798
rocG
NAD-specific glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
  
 
 0.788
Your Current Organism:
Paenibacillus macerans
NCBI taxonomy Id: 44252
Other names: ATCC 8244, Aerobacillus macerans, BCRC 14680, Bacillus macerans, Bactrillum macerans, CCM 2012, CCRC 14680, CCRC:14680, CCUG 7423, CFBP 4253, CIP 66.19, DSM 24, HAMBI 636, IAM 12467, IFO 15307, JCM 2500, LMG 13281, LMG 6324, LMG:13281, LMG:6324, NBRC 15307, NCCB 48019, NCIB 9368, NCIMB 9368, NCTC 6355, NRRL B-172, NRRL B-394, NRRL B-4267, P. macerans, VKM B-506, Zymobacillus macerans
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