STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DJ90_3465Lipoyltrans: lipoyltransferase and lipoate-ligase family protein. (334 aa)    
Predicted Functional Partners:
lipA
Lipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
 
 
 0.991
gcvH
Glycine cleavage system H protein; Is also involved in protein lipoylation via its role as an octanoyl/lipoyl carrier protein intermediate; Belongs to the GcvH family.
 
 
 0.988
pdhC
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex.
 
 0.926
DJ90_4341
2-oxoacid dehydrogenases acyltransferase family protein.
 
 0.908
DJ90_3081
2-oxoacid dehydrogenases acyltransferase family protein.
 
 0.904
lipB
Lipoyl(octanoyl) transferase; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
   
 0.903
lpdA-3
lipoamide_DH: dihydrolipoyl dehydrogenase.
 
 
 0.860
pdhB
Pyruvate dehydrogenase E1 component subunit beta.
 
 
 0.841
DJ90_4342
Transketolase, C-terminal domain protein.
 
 
 0.828
bfmBAB
2-oxoisovalerate dehydrogenase subunit beta.
 
 
 0.823
Your Current Organism:
Paenibacillus macerans
NCBI taxonomy Id: 44252
Other names: ATCC 8244, Aerobacillus macerans, BCRC 14680, Bacillus macerans, Bactrillum macerans, CCM 2012, CCRC 14680, CCRC:14680, CCUG 7423, CFBP 4253, CIP 66.19, DSM 24, HAMBI 636, IAM 12467, IFO 15307, JCM 2500, LMG 13281, LMG 6324, LMG:13281, LMG:6324, NBRC 15307, NCCB 48019, NCIB 9368, NCIMB 9368, NCTC 6355, NRRL B-172, NRRL B-394, NRRL B-4267, P. macerans, VKM B-506, Zymobacillus macerans
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