STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fmtmethionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. (323 aa)    
Predicted Functional Partners:
sun
Ribosomal RNA small subunit methyltransferase B; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.
  
  
 0.998
def
Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
 0.985
DJ90_3584
Homocysteine S-methyltransferase family protein.
    
 0.963
folD
Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.
 
 
 0.955
priA
Primosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily.
 
    0.925
DJ90_3595
Stage II sporulation E family protein.
  
   0.924
metG
methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily.
    
 0.911
pruA
D1pyr5carbox2: putative delta-1-pyrroline-5-carboxylate dehydrogenase.
 
    
 0.893
purN
Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
    
0.888
DJ90_6130
3-beta hydroxysteroid dehydrogenase/isomerase family protein.
   
  0.888
Your Current Organism:
Paenibacillus macerans
NCBI taxonomy Id: 44252
Other names: ATCC 8244, Aerobacillus macerans, BCRC 14680, Bacillus macerans, Bactrillum macerans, CCM 2012, CCRC 14680, CCRC:14680, CCUG 7423, CFBP 4253, CIP 66.19, DSM 24, HAMBI 636, IAM 12467, IFO 15307, JCM 2500, LMG 13281, LMG 6324, LMG:13281, LMG:6324, NBRC 15307, NCCB 48019, NCIB 9368, NCIMB 9368, NCTC 6355, NRRL B-172, NRRL B-394, NRRL B-4267, P. macerans, VKM B-506, Zymobacillus macerans
Server load: low (10%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.