STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EYD78019.12-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase. (189 aa)    
Predicted Functional Partners:
EYD77784.1
Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.
 
 0.999
EYD77785.1
Dihydroneopterin aldolase / delta 1-pyrroline-5-carboxylate synthetase.
 
 
 0.996
ribB
3,4-dihydroxy-2-butanone 4-phosphate synthase / GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.
 
  
 0.927
EYD78158.1
Dihydrofolate synthase / Folylpolyglutamate synthase; Belongs to the folylpolyglutamate synthase family.
 
 
 0.851
EYD75374.1
tRNA nucleotidyltransferase; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.
  
    0.827
EYD77612.1
Para-aminobenzoate synthase, aminase component.
 
 
 0.791
trpE
Anthranilate synthase, aminase component; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high c [...]
 
 
 0.725
EYD78017.1
In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
    
  0.720
EYD78020.1
Hypothetical protein; Mll7752.
       0.706
EYD75917.1
Diaminohydroxyphosphoribosylaminopyrimidine deaminase / 5-amino-6-uracil reductase; 5-phosphoribosylamino; overlaps another CDS with the same product name.
 
  
 0.685
Your Current Organism:
Rubellimicrobium mesophilum
NCBI taxonomy Id: 442562
Other names: R. mesophilum DSM 19309, Rubellimicrobium mesophilum DSM 19309, Rubellimicrobium sp. MSL-20
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