node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EYD76516.1 | EYD77538.1 | Rumeso_01937 | Rumeso_00704 | Histidinol-phosphate aminotransferase / Aromatic-amino-acid aminotransferase. | ATP phosphoribosyltransferase regulatory subunit. | 0.826 |
EYD76516.1 | EYD77539.1 | Rumeso_01937 | Rumeso_00705 | Histidinol-phosphate aminotransferase / Aromatic-amino-acid aminotransferase. | ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. | 0.887 |
EYD76516.1 | hisA | Rumeso_01937 | Rumeso_02116 | Histidinol-phosphate aminotransferase / Aromatic-amino-acid aminotransferase. | Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase. | 0.890 |
EYD76516.1 | hisD | Rumeso_01937 | Rumeso_00916 | Histidinol-phosphate aminotransferase / Aromatic-amino-acid aminotransferase. | Putative histidinol dehydrogenase (but probably not); Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. | 0.902 |
EYD76516.1 | hisE | Rumeso_01937 | Rumeso_02120 | Histidinol-phosphate aminotransferase / Aromatic-amino-acid aminotransferase. | Phosphoribosyl-ATP pyrophosphatase. | 0.852 |
EYD76516.1 | hisF | Rumeso_01937 | Rumeso_02119 | Histidinol-phosphate aminotransferase / Aromatic-amino-acid aminotransferase. | Imidazole glycerol phosphate synthase cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. | 0.948 |
EYD76516.1 | hisH | Rumeso_01937 | Rumeso_02113 | Histidinol-phosphate aminotransferase / Aromatic-amino-acid aminotransferase. | Imidazole glycerol phosphate synthase amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. | 0.960 |
EYD76516.1 | hisI | Rumeso_01937 | Rumeso_04620 | Histidinol-phosphate aminotransferase / Aromatic-amino-acid aminotransferase. | Phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. | 0.930 |
EYD77538.1 | EYD76516.1 | Rumeso_00704 | Rumeso_01937 | ATP phosphoribosyltransferase regulatory subunit. | Histidinol-phosphate aminotransferase / Aromatic-amino-acid aminotransferase. | 0.826 |
EYD77538.1 | EYD77539.1 | Rumeso_00704 | Rumeso_00705 | ATP phosphoribosyltransferase regulatory subunit. | ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. | 0.999 |
EYD77538.1 | hisA | Rumeso_00704 | Rumeso_02116 | ATP phosphoribosyltransferase regulatory subunit. | Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase. | 0.950 |
EYD77538.1 | hisC | Rumeso_00704 | Rumeso_00719 | ATP phosphoribosyltransferase regulatory subunit. | Biosynthetic Aromatic amino acid aminotransferase beta; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | 0.823 |
EYD77538.1 | hisD | Rumeso_00704 | Rumeso_00916 | ATP phosphoribosyltransferase regulatory subunit. | Putative histidinol dehydrogenase (but probably not); Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. | 0.778 |
EYD77538.1 | hisE | Rumeso_00704 | Rumeso_02120 | ATP phosphoribosyltransferase regulatory subunit. | Phosphoribosyl-ATP pyrophosphatase. | 0.992 |
EYD77538.1 | hisF | Rumeso_00704 | Rumeso_02119 | ATP phosphoribosyltransferase regulatory subunit. | Imidazole glycerol phosphate synthase cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. | 0.975 |
EYD77538.1 | hisH | Rumeso_00704 | Rumeso_02113 | ATP phosphoribosyltransferase regulatory subunit. | Imidazole glycerol phosphate synthase amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. | 0.947 |
EYD77538.1 | hisI | Rumeso_00704 | Rumeso_04620 | ATP phosphoribosyltransferase regulatory subunit. | Phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. | 0.967 |
EYD77539.1 | EYD76516.1 | Rumeso_00705 | Rumeso_01937 | ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. | Histidinol-phosphate aminotransferase / Aromatic-amino-acid aminotransferase. | 0.887 |
EYD77539.1 | EYD77538.1 | Rumeso_00705 | Rumeso_00704 | ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. | ATP phosphoribosyltransferase regulatory subunit. | 0.999 |
EYD77539.1 | hisA | Rumeso_00705 | Rumeso_02116 | ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. | Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase. | 0.977 |