STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EYD76510.15,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (286 aa)    
Predicted Functional Partners:
EYD76767.1
Betaine--homocysteine S-methyltransferase.
 
 
 0.960
EYD76609.1
Pterin-binding protein enzyme domain protein.
 
 
 0.955
EYD77210.1
Methionine synthase II (Cobalamin-independent).
  
 0.937
metAA
Homoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family.
  
  
 0.933
rpsF
SSU ribosomal protein S6p; Binds together with S18 to 16S ribosomal RNA.
  
 
 0.930
folD
Methylenetetrahydrofolate dehydrogenase (NADP+); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.
    
 0.913
EYD76610.1
5,10-methylenetetrahydrofolate reductase.
     
 0.880
EYD77879.1
Aminomethyltransferase (glycine cleavage system T protein).
  
 
 0.872
EYD77010.1
Aminomethyltransferase (glycine cleavage system T protein).
  
 
 0.872
metK
S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
  
 
 0.856
Your Current Organism:
Rubellimicrobium mesophilum
NCBI taxonomy Id: 442562
Other names: R. mesophilum DSM 19309, Rubellimicrobium mesophilum DSM 19309, Rubellimicrobium sp. MSL-20
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