node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BLA_0390 | infB | BLA_0390 | BLA_0392 | Conserved hypothetical protein. | Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. | 0.595 |
BLA_0390 | nusA | BLA_0390 | BLA_0391 | Conserved hypothetical protein. | N utilization substance-like protein; Participates in both transcription termination and antitermination. | 0.718 |
BLA_0390 | rbfA | BLA_0390 | BLA_0393 | Conserved hypothetical protein. | Ribosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. | 0.542 |
BLA_0390 | ribF | BLA_0390 | BLA_0395 | Conserved hypothetical protein. | Riboflavin kinase; COG0196: FAD synthase. | 0.495 |
BLA_0390 | truB | BLA_0390 | BLA_0394 | Conserved hypothetical protein. | tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily. | 0.542 |
cdsA | ribF | BLA_1299 | BLA_0395 | Probable phosphatidate cytidylyltransferase; COG0575: CDP-diglyceride synthetase. | Riboflavin kinase; COG0196: FAD synthase. | 0.528 |
coaD | ribF | BLA_0269 | BLA_0395 | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | Riboflavin kinase; COG0196: FAD synthase. | 0.627 |
folC | folD | BLA_0748 | BLA_1499 | COG0285: Folylpolyglutamate synthase. | Bifunctional protein FolD; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.708 |
folC | ribF | BLA_0748 | BLA_0395 | COG0285: Folylpolyglutamate synthase. | Riboflavin kinase; COG0196: FAD synthase. | 0.680 |
folD | folC | BLA_1499 | BLA_0748 | Bifunctional protein FolD; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | COG0285: Folylpolyglutamate synthase. | 0.708 |
folD | ribF | BLA_1499 | BLA_0395 | Bifunctional protein FolD; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | Riboflavin kinase; COG0196: FAD synthase. | 0.516 |
infB | BLA_0390 | BLA_0392 | BLA_0390 | Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. | Conserved hypothetical protein. | 0.595 |
infB | nusA | BLA_0392 | BLA_0391 | Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. | N utilization substance-like protein; Participates in both transcription termination and antitermination. | 0.974 |
infB | rbfA | BLA_0392 | BLA_0393 | Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. | Ribosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. | 0.999 |
infB | ribF | BLA_0392 | BLA_0395 | Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. | Riboflavin kinase; COG0196: FAD synthase. | 0.688 |
infB | rpsO | BLA_0392 | BLA_0306 | Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. | Ribosomal protein S15; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA. | 0.999 |
infB | truB | BLA_0392 | BLA_0394 | Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. | tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily. | 0.983 |
nusA | BLA_0390 | BLA_0391 | BLA_0390 | N utilization substance-like protein; Participates in both transcription termination and antitermination. | Conserved hypothetical protein. | 0.718 |
nusA | infB | BLA_0391 | BLA_0392 | N utilization substance-like protein; Participates in both transcription termination and antitermination. | Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. | 0.974 |
nusA | rbfA | BLA_0391 | BLA_0393 | N utilization substance-like protein; Participates in both transcription termination and antitermination. | Ribosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. | 0.743 |