STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BLA_0991Histidine kinase sensor of two-component system; COG4585: Signal transduction histidine kinase. (847 aa)    
Predicted Functional Partners:
BLA_0990
Response regulator of two-component system; COG2197: Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain.
 
 0.962
BLA_0919
Response regulator of two-component system; COG2197: Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain.
 
 
 0.873
BLA_1085
Response regulator of two-component system; COG2197: Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain.
 
 
 0.869
BLA_0407
Response regulator of two-component system; COG2197: Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain.
 
 
 0.861
BLA_0749
COG2197: Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain.
 
 
 0.842
BLA_0920
Histidine kinase sensor of two-component system; COG4585: Signal transduction histidine kinase.
  
     0.752
pap
Proline iminopeptidase; COG0596: Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).
       0.712
proC
Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
 
     0.688
ychF
Putative GTP-binding protein; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
       0.573
BLA_0408
Possible histidine kinase sensor of two component system; COG4585: Signal transduction histidine kinase.
 
    0.500
Your Current Organism:
Bifidobacterium animalis
NCBI taxonomy Id: 442563
Other names: B. animalis subsp. lactis AD011, Bifidobacterium animalis subsp. lactis AD011, Bifidobacterium animalis subsp. lactis str. AD011, Bifidobacterium animalis subsp. lactis strain AD011, Bifidobacterium lactis AD011
Server load: low (18%) [HD]