node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BLA_0718 | dnaN | BLA_0718 | BLA_0002 | Possible exodeoxyribonuclease; COG0708: Exonuclease III. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.935 |
BLA_0718 | polA | BLA_0718 | BLA_1491 | Possible exodeoxyribonuclease; COG0708: Exonuclease III. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.999 |
BLA_1107 | polA | BLA_1107 | BLA_1491 | COG1061: DNA or RNA helicases of superfamily II. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.928 |
BLA_1489 | BLA_1490 | BLA_1489 | BLA_1490 | Possible pyrophosphate-releasing NTPase in MutT family; COG0494: NTP pyrophosphohydrolases including oxidative damage repair enzymes. | Putative NGG1-interacting factor 3; COG0327: Uncharacterized conserved protein. | 0.853 |
BLA_1489 | BLA_1492 | BLA_1489 | BLA_1492 | Possible pyrophosphate-releasing NTPase in MutT family; COG0494: NTP pyrophosphohydrolases including oxidative damage repair enzymes. | COG3707: Response regulator with putative antiterminator output domain. | 0.686 |
BLA_1489 | glgX-2 | BLA_1489 | BLA_1488 | Possible pyrophosphate-releasing NTPase in MutT family; COG0494: NTP pyrophosphohydrolases including oxidative damage repair enzymes. | Glycogen debranching enzyme GlgX; COG1523: Type II secretory pathway, pullulanase PulA and related glycosidases; Belongs to the glycosyl hydrolase 13 family. | 0.761 |
BLA_1489 | polA | BLA_1489 | BLA_1491 | Possible pyrophosphate-releasing NTPase in MutT family; COG0494: NTP pyrophosphohydrolases including oxidative damage repair enzymes. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.790 |
BLA_1490 | BLA_1489 | BLA_1490 | BLA_1489 | Putative NGG1-interacting factor 3; COG0327: Uncharacterized conserved protein. | Possible pyrophosphate-releasing NTPase in MutT family; COG0494: NTP pyrophosphohydrolases including oxidative damage repair enzymes. | 0.853 |
BLA_1490 | BLA_1492 | BLA_1490 | BLA_1492 | Putative NGG1-interacting factor 3; COG0327: Uncharacterized conserved protein. | COG3707: Response regulator with putative antiterminator output domain. | 0.686 |
BLA_1490 | glgX-2 | BLA_1490 | BLA_1488 | Putative NGG1-interacting factor 3; COG0327: Uncharacterized conserved protein. | Glycogen debranching enzyme GlgX; COG1523: Type II secretory pathway, pullulanase PulA and related glycosidases; Belongs to the glycosyl hydrolase 13 family. | 0.761 |
BLA_1490 | polA | BLA_1490 | BLA_1491 | Putative NGG1-interacting factor 3; COG0327: Uncharacterized conserved protein. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.793 |
BLA_1492 | BLA_1489 | BLA_1492 | BLA_1489 | COG3707: Response regulator with putative antiterminator output domain. | Possible pyrophosphate-releasing NTPase in MutT family; COG0494: NTP pyrophosphohydrolases including oxidative damage repair enzymes. | 0.686 |
BLA_1492 | BLA_1490 | BLA_1492 | BLA_1490 | COG3707: Response regulator with putative antiterminator output domain. | Putative NGG1-interacting factor 3; COG0327: Uncharacterized conserved protein. | 0.686 |
BLA_1492 | glgX-2 | BLA_1492 | BLA_1488 | COG3707: Response regulator with putative antiterminator output domain. | Glycogen debranching enzyme GlgX; COG1523: Type II secretory pathway, pullulanase PulA and related glycosidases; Belongs to the glycosyl hydrolase 13 family. | 0.635 |
BLA_1492 | polA | BLA_1492 | BLA_1491 | COG3707: Response regulator with putative antiterminator output domain. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.728 |
dinB | dnaN | BLA_0349 | BLA_0002 | DNA-damage-inducible protein P; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.874 |
dinB | polA | BLA_0349 | BLA_1491 | DNA-damage-inducible protein P; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.724 |
dinB | recA | BLA_0349 | BLA_0934 | DNA-damage-inducible protein P; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. | Protein RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.854 |
dnaN | BLA_0718 | BLA_0002 | BLA_0718 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Possible exodeoxyribonuclease; COG0708: Exonuclease III. | 0.935 |
dnaN | dinB | BLA_0002 | BLA_0349 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA-damage-inducible protein P; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. | 0.874 |