STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nadE-2NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family. (329 aa)    
Predicted Functional Partners:
GM18_0918
PFAM: phosphopantetheine-binding; KEGG: gbm:Gbem_1084 hypothetical protein.
 
   
 0.929
nadE
NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family.
  
  
 
0.924
nadD
Nicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
  
 
 0.921
nadK
NAD(+) kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
    
 0.916
GM18_2328
KEGG: gem:GM21_1747 NAD(+) diphosphatase; PFAM: NUDIX hydrolase; NADH pyrophosphatase-like; Belongs to the Nudix hydrolase family.
  
 
 0.906
nadE-3
NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family.
  
  
 
0.902
GM18_1670
KEGG: geo:Geob_2950 hypothetical protein.
 
   
 0.789
GM18_3810
PFAM: phosphopantetheine-binding; KEGG: gem:GM21_0559 acyl carrier protein.
 
   
 0.775
GM18_0919
KEGG: gbm:Gbem_1085 acetyltransferase (isoleucine patch superfamily)-like protein.
 
 
 
 0.766
GM18_1672
KEGG: geo:Geob_2948 asparagine synthase (glutamine-hydrolyzing); TIGRFAM: asparagine synthase (glutamine-hydrolyzing); PFAM: asparagine synthase.
 
   
 0.672
Your Current Organism:
Geobacter sp. M18
NCBI taxonomy Id: 443143
Other names: G. sp. M18
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