STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GM18_2596KEGG: gem:GM21_1511 peptidase M16 domain protein; PFAM: peptidase M16 domain protein. (424 aa)    
Predicted Functional Partners:
nuoC
NADH dehydrogenase I, D subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I 30 kDa subunit family. In the C-terminal section; belongs to the complex I 49 kDa subunit family.
  
 
 0.990
GM18_1858
KEGG: ppd:Ppro_3516 NADH dehydrogenase (quinone); PFAM: Respiratory-chain NADH dehydrogenase domain 51 kDa subunit; NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding; Soluble ligand binding domain.
  
 
 0.967
GM18_0922
Rieske (2Fe-2S) iron-sulfur domain protein; PFAM: Rieske [2Fe-2S] iron-sulphur domain; Cytochrome b6-f complex Fe-S subunit; KEGG: gem:GM21_3173 Rieske (2Fe-2S) domain protein.
  
 0.932
GM18_4480
PFAM: Rieske [2Fe-2S] iron-sulphur domain; KEGG: gem:GM21_4116 Rieske (2Fe-2S) domain protein.
   
 0.922
GM18_0152
KEGG: gbm:Gbem_0175 NADH dehydrogenase subunit G; TIGRFAM: NADH-quinone oxidoreductase, chain G; PFAM: NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding; ferredoxin.
   
 
 0.903
GM18_0529
KEGG: gem:GM21_3627 NAD-dependent epimerase/dehydratase.
   
 
 0.866
GM18_3666
KEGG: gbm:Gbem_0686 peptidase M16 domain protein; PFAM: peptidase M16 domain protein.
  
0.834
GM18_0042
Cytochrome c oxidase, subunit II; Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).
   
 
 0.813
GM18_0040
PFAM: cytochrome c oxidase subunit III; KEGG: gbm:Gbem_0044 cytochrome c oxidase subunit III.
   
 
 0.808
GM18_0039
Cytochrome c oxidase, subunit I; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
   
 
 0.807
Your Current Organism:
Geobacter sp. M18
NCBI taxonomy Id: 443143
Other names: G. sp. M18
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