STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ruvBHolliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. (337 aa)    
Predicted Functional Partners:
ruvA
Holliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.
 
 
 0.998
ruvC
Crossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.
 
 
 0.971
queA
S-adenosylmethionine/tRNA-ribosyltransferase- isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
  
  
 0.861
GM21_0889
KEGG: gbm:Gbem_3356 hypothetical protein.
  
    0.803
GM21_2480
KEGG: gbm:Gbem_1767 PEP-Cterm system TPR-repeat lipoprotein; TIGRFAM: PEP-CTERM system TPR-repeat lipoprotein; PFAM: Tetratricopeptide TPR_2 repeat protein; TPR repeat-containing protein; SMART: Tetratricopeptide domain protein.
  
    0.777
GM21_0929
PFAM: Chromosomal replication initiator DnaA; KEGG: gbm:Gbem_3317 chromosomal replication initiator DnaA; Belongs to the DnaA family.
 
  
 0.664
GM21_4056
PFAM: cell divisionFtsK/SpoIIIE; SMART: AAA ATPase; KEGG: gbm:Gbem_3970 cell divisionFtsK/SpoIIIE.
 
  
 0.664
GM21_3842
KEGG: gbm:Gbem_3758 rod binding protein-like protein.
    
   0.657
fliE
TIGRFAM: flagellar hook-basal body complex subunit FliE; PFAM: flagellar hook-basal body complex protein FliE; KEGG: gbm:Gbem_3839 flagellar hook-basal body complex subunit FliE.
    
   0.657
pheT
TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit; KEGG: gbm:Gbem_1995 phenylalanyl-tRNA synthetase, beta subunit.
 
   
 0.655
Your Current Organism:
Geobacter sp. M21
NCBI taxonomy Id: 443144
Other names: G. sp. M21
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.