STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GM21_3530Heavy metal sensor signal transduction histidine kinase; Member of a two-component regulatory system. (484 aa)    
Predicted Functional Partners:
GM21_3531
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: gbm:Gbem_3465 two component transcriptional regulator, winged helix family.
 
 0.996
GM21_3720
KEGG: gbm:Gbem_3615 two component heavy metal response transcriptional regulator, winged helix family; TIGRFAM: heavy metal response regulator; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver.
 
 0.985
GM21_2357
Putative PAS/PAC sensor protein; KEGG: sat:SYN_00875 response regulator; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; PAS fold-3 domain protein; SMART: response regulator receiver; PAC repeat-containing protein; PAS domain containing protein.
 
 
 0.952
GM21_3721
Heavy metal sensor signal transduction histidine kinase; Member of a two-component regulatory system.
  
  
 
0.917
GM21_1570
Transcriptional regulator, XRE family; PFAM: response regulator receiver; helix-turn-helix domain protein; SMART: response regulator receiver; helix-turn-helix domain protein; KEGG: gbm:Gbem_2665 transcriptional regulator, XRE family.
 
 
 0.914
GM21_0693
PFAM: response regulator receiver; heat shock protein DnaJ domain protein; SMART: response regulator receiver; Tetratricopeptide domain protein; KEGG: gbm:Gbem_0681 response regulator receiver protein.
 
 
 0.912
GM21_0975
PFAM: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; SMART: response regulator receiver; histidine kinase A domain protein; ATP-binding region ATPase domain protein; KEGG: gbm:Gbem_3274 response regulator receiver sensor signal transduction histidine kinase.
 
 
0.899
GM21_2550
PFAM: response regulator receiver; SMART: response regulator receiver; KEGG: gbm:Gbem_1663 response regulator receiver protein.
 
 
 0.886
GM21_0227
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: gbm:Gbem_0243 two component transcriptional regulator, winged helix family.
 
 
 0.860
GM21_2079
KEGG: gbm:Gbem_2137 multi-sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; Cache domain protein; PAS fold domain protein; PAS fold-4 domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; PAC repeat-containing protein; PAS domain containing protein.
 
 
0.850
Your Current Organism:
Geobacter sp. M21
NCBI taxonomy Id: 443144
Other names: G. sp. M21
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.