node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EDM46627.1 | EDM48439.1 | MDG893_19509 | MDG893_04597 | COG0705 Uncharacterized membrane protein (homolog of Drosophila rhomboid). | COG0212 5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. | 0.623 |
EDM48118.1 | EDM48439.1 | MDG893_03555 | MDG893_04597 | COG0705 Uncharacterized membrane protein (homolog of Drosophila rhomboid). | COG0212 5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. | 0.623 |
EDM48439.1 | EDM46627.1 | MDG893_04597 | MDG893_19509 | COG0212 5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. | COG0705 Uncharacterized membrane protein (homolog of Drosophila rhomboid). | 0.623 |
EDM48439.1 | EDM48118.1 | MDG893_04597 | MDG893_03555 | COG0212 5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. | COG0705 Uncharacterized membrane protein (homolog of Drosophila rhomboid). | 0.623 |
EDM48439.1 | EDM48904.1 | MDG893_04597 | MDG893_03055 | COG0212 5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. | Hypothetical protein; COG2856 Predicted Zn peptidase. | 0.642 |
EDM48439.1 | EDM49651.1 | MDG893_04597 | MDG893_10636 | COG0212 5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. | COG0705 Uncharacterized membrane protein (homolog of Drosophila rhomboid). | 0.623 |
EDM48439.1 | fhs | MDG893_04597 | MDG893_11081 | COG0212 5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. | Formate--tetrahydrofolate ligase; COG2759 Formyltetrahydrofolate synthetase; Belongs to the formate--tetrahydrofolate ligase family. | 0.668 |
EDM48439.1 | folD | MDG893_04597 | MDG893_00115 | COG0212 5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. | Methylenetetrahydrofolate dehydrogenase (NADP+); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.978 |
EDM48439.1 | pheT | MDG893_04597 | MDG893_10566 | COG0212 5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. | phenylalanyl-tRNA synthetase beta subunit; COG0073 EMAP domain; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.624 |
EDM48439.1 | purH | MDG893_04597 | MDG893_04679 | COG0212 5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. | Bifunctional purine biosynthesis protein PurH; COG0138 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful). | 0.556 |
EDM48439.1 | purN | MDG893_04597 | MDG893_09251 | COG0212 5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.979 |
EDM48439.1 | purT | MDG893_04597 | MDG893_09531 | COG0212 5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. | Phosphoribosylglycinamide formyltransferase 2; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family. | 0.969 |
EDM48904.1 | EDM48439.1 | MDG893_03055 | MDG893_04597 | Hypothetical protein; COG2856 Predicted Zn peptidase. | COG0212 5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. | 0.642 |
EDM48904.1 | fhs | MDG893_03055 | MDG893_11081 | Hypothetical protein; COG2856 Predicted Zn peptidase. | Formate--tetrahydrofolate ligase; COG2759 Formyltetrahydrofolate synthetase; Belongs to the formate--tetrahydrofolate ligase family. | 0.698 |
EDM48904.1 | folD | MDG893_03055 | MDG893_00115 | Hypothetical protein; COG2856 Predicted Zn peptidase. | Methylenetetrahydrofolate dehydrogenase (NADP+); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.705 |
EDM48904.1 | purH | MDG893_03055 | MDG893_04679 | Hypothetical protein; COG2856 Predicted Zn peptidase. | Bifunctional purine biosynthesis protein PurH; COG0138 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful). | 0.532 |
EDM48904.1 | purN | MDG893_03055 | MDG893_09251 | Hypothetical protein; COG2856 Predicted Zn peptidase. | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.525 |
EDM49651.1 | EDM48439.1 | MDG893_10636 | MDG893_04597 | COG0705 Uncharacterized membrane protein (homolog of Drosophila rhomboid). | COG0212 5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. | 0.623 |
fhs | EDM48439.1 | MDG893_11081 | MDG893_04597 | Formate--tetrahydrofolate ligase; COG2759 Formyltetrahydrofolate synthetase; Belongs to the formate--tetrahydrofolate ligase family. | COG0212 5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. | 0.668 |
fhs | EDM48904.1 | MDG893_11081 | MDG893_03055 | Formate--tetrahydrofolate ligase; COG2759 Formyltetrahydrofolate synthetase; Belongs to the formate--tetrahydrofolate ligase family. | Hypothetical protein; COG2856 Predicted Zn peptidase. | 0.698 |