node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EDM46866.1 | EDM47340.1 | MDG893_13209 | MDG893_04799 | COG0067 Glutamate synthase domain 1. | COG1445 Phosphotransferase system fructose-specific component IIB. | 0.403 |
EDM46866.1 | EDM49066.1 | MDG893_13209 | MDG893_06514 | COG0067 Glutamate synthase domain 1. | Hypothetical protein; COG0477 Permeases of the major facilitator superfamily. | 0.454 |
EDM46866.1 | thyA | MDG893_13209 | MDG893_12590 | COG0067 Glutamate synthase domain 1. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.489 |
EDM47106.1 | EDM49066.1 | MDG893_11974 | MDG893_06514 | Hypothetical protein. | Hypothetical protein; COG0477 Permeases of the major facilitator superfamily. | 0.559 |
EDM47340.1 | EDM46866.1 | MDG893_04799 | MDG893_13209 | COG1445 Phosphotransferase system fructose-specific component IIB. | COG0067 Glutamate synthase domain 1. | 0.403 |
EDM47340.1 | EDM49066.1 | MDG893_04799 | MDG893_06514 | COG1445 Phosphotransferase system fructose-specific component IIB. | Hypothetical protein; COG0477 Permeases of the major facilitator superfamily. | 0.416 |
EDM48581.1 | EDM49066.1 | MDG893_18602 | MDG893_06514 | Hypothetical protein. | Hypothetical protein; COG0477 Permeases of the major facilitator superfamily. | 0.455 |
EDM49066.1 | EDM46866.1 | MDG893_06514 | MDG893_13209 | Hypothetical protein; COG0477 Permeases of the major facilitator superfamily. | COG0067 Glutamate synthase domain 1. | 0.454 |
EDM49066.1 | EDM47106.1 | MDG893_06514 | MDG893_11974 | Hypothetical protein; COG0477 Permeases of the major facilitator superfamily. | Hypothetical protein. | 0.559 |
EDM49066.1 | EDM47340.1 | MDG893_06514 | MDG893_04799 | Hypothetical protein; COG0477 Permeases of the major facilitator superfamily. | COG1445 Phosphotransferase system fructose-specific component IIB. | 0.416 |
EDM49066.1 | EDM48581.1 | MDG893_06514 | MDG893_18602 | Hypothetical protein; COG0477 Permeases of the major facilitator superfamily. | Hypothetical protein. | 0.455 |
EDM49066.1 | EDM49091.1 | MDG893_06514 | MDG893_06835 | Hypothetical protein; COG0477 Permeases of the major facilitator superfamily. | Hypothetical protein. | 0.574 |
EDM49066.1 | aroC | MDG893_06514 | MDG893_06509 | Hypothetical protein; COG0477 Permeases of the major facilitator superfamily. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.546 |
EDM49066.1 | ndk | MDG893_06514 | MDG893_08155 | Hypothetical protein; COG0477 Permeases of the major facilitator superfamily. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.486 |
EDM49066.1 | prmB | MDG893_06514 | MDG893_06504 | Hypothetical protein; COG0477 Permeases of the major facilitator superfamily. | Putative DNA methylase; Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue; Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily. | 0.497 |
EDM49066.1 | thyA | MDG893_06514 | MDG893_12590 | Hypothetical protein; COG0477 Permeases of the major facilitator superfamily. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.486 |
EDM49066.1 | tmk | MDG893_06514 | MDG893_00230 | Hypothetical protein; COG0477 Permeases of the major facilitator superfamily. | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.477 |
EDM49091.1 | EDM49066.1 | MDG893_06835 | MDG893_06514 | Hypothetical protein. | Hypothetical protein; COG0477 Permeases of the major facilitator superfamily. | 0.574 |
aroC | EDM49066.1 | MDG893_06509 | MDG893_06514 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Hypothetical protein; COG0477 Permeases of the major facilitator superfamily. | 0.546 |
aroC | prmB | MDG893_06509 | MDG893_06504 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Putative DNA methylase; Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue; Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily. | 0.801 |