STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
htpGMolecular chaperone, HSP90 family protein; Molecular chaperone. Has ATPase activity. (630 aa)    
Predicted Functional Partners:
dnaK
Molecular chaperone; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 0.999
EDM46271.1
Hypothetical protein.
    
 0.996
dnaJ
DnaJ-class molecular chaperone with C-terminal Zn finger domain; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of A [...]
  
 0.994
EDM47874.1
COG0545 FKBP-type peptidyl-prolyl cis-trans isomerases 1.
   
 0.988
EDM48838.1
Heat shock protein DnaJ-like protein; COG2214 DnaJ-class molecular chaperone.
  
 0.983
EDM46560.1
COG2214 DnaJ-class molecular chaperone.
  
 0.983
EDM47821.1
Hypothetical protein; COG2214 DnaJ-class molecular chaperone.
  
 0.983
EDM47423.1
Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family protein; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.
  
 0.974
EDM49309.1
Peptidyl-prolyl cis-trans isomerase A; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.
  
 0.974
groL
Chaperonin GroEL (HSP60 family) protein; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
   
 
 0.962
Your Current Organism:
Marinobacter algicola
NCBI taxonomy Id: 443152
Other names: M. algicola DG893, Marinobacter algicola DG893, Marinobacter algicola str. DG893, Marinobacter algicola strain DG893, Marinobacter sp. DG893
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.