STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDM49551.1Transcriptional regulator involved in mercury resistance operon; COG0789 Predicted transcriptional regulators. (133 aa)    
Predicted Functional Partners:
EDM46866.1
COG0067 Glutamate synthase domain 1.
    
 0.826
EDM49540.1
COG0789 Predicted transcriptional regulators.
  
     0.772
EDM49186.1
Transcriptional regulator, MerR family protein; COG0789 Predicted transcriptional regulators.
  
     0.753
rpoD
Sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
   
 
 0.737
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.655
EDM48016.1
Two-component response regulator; COG2202 FOG: PAS/PAC domain.
    
 0.629
EDM48838.1
Heat shock protein DnaJ-like protein; COG2214 DnaJ-class molecular chaperone.
  
 
 0.609
EDM46560.1
COG2214 DnaJ-class molecular chaperone.
  
 
 0.609
dnaJ
DnaJ-class molecular chaperone with C-terminal Zn finger domain; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of A [...]
  
 
 0.609
EDM47821.1
Hypothetical protein; COG2214 DnaJ-class molecular chaperone.
  
 
 0.609
Your Current Organism:
Marinobacter algicola
NCBI taxonomy Id: 443152
Other names: M. algicola DG893, Marinobacter algicola DG893, Marinobacter algicola str. DG893, Marinobacter algicola strain DG893, Marinobacter sp. DG893
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.